Fermentation & Downstream Development and Optimization

Flexible, best-in-class bioprocess support as the extension of your lab and pilot

Fermentation Development and Scale Up

Fermentation Development and Scale Up

  • Precise development for batch, fed-batch and continuous aerobic fermentation.
  • Expertise across yeast, bacteria, and fungal host platforms.
  • Assets include fermenters at 16x1.5L, 3x15L, 20L, 75L, 500L, and 1500L scale.
  • Advanced control and online monitoring capabilities for process development. 
Fermentation Development and Scale Up
Downstream Process Development
Downstream Process Development

Downstream Process Development

  • Expertise on separation and purification for molecules with challenging stabilization and enriching processes to ensure scalability.
  • Formats include solid/liquid, liquid/liquid, and slurries.
  • Assets include floor centrifuges, disc stack centrifuges, decanter, multi-stage TFFs, ceramic memebrane filtrations, freeze dryers, spray dryers, oven dryers, and tray dryers.
  • Strong expertise on industrial-scale cell lysis, including homogenizers, bead mills, and chemical lysis.
Analytical Lab

Analytical Lab

  • Full supporting functions for in-process metabolites testing, DSP sample stream testing, and final product specs analysis. 
  • Assets include Roche Cedex Bio Analzyer, Cedex Bio HT Analzyer, HPLC, UV, SDS PAGE, Western Blot, Enzyme and Protein Assays. 
  • Close partnership with FDA certified analytical labs and institutes. 
Analytical Lab
Tech Transfer to CMO
Tech Transfer to CMO

Tech Transfer to CMO

  • Extensive and in-depth network with CMOs, collaborating with the best fit capabilities for each client’s needs.
  • Significant experience overseeing tech transfer to manufacturing to ensure smooth production.