Full-suite fermentation and downstream processing services at benchtop and pilot scale.
Strain testing in conditions replicating commercial manufacturingMedia and process optimizationGRAS oriented process development
Wide range of DSP unit operations optimization and scaling Protein purification by multi-stage TFFSpray drying development and scale up
Expertise in approval process with FDAProcess towards safety approvalCritical control point identification in process flow
Connections to large-scale producers, negotiation assistance, and tech transfer oversight for smooth transition to industrial-scale production
A one-stop shop to bring your process to commercial scale.
Vessels ranging from 1.5L to 1,500L for stepwise scale up
Solid/liquid, liquid/liquid, slurries. Centrifuges, homogenizer, bead mill, chemical lysis. Strong expertise in industrial-scale cell lysis
Multi-stage TFFs, freeze dryers, spray dryers
HPLC, GC, UV, off-gas, mass spectrometer
"[We are] three months ahead of schedule, having completed scale up in November with the support of Boston Bio...and the University of Illinois Integrated Bioprocessing Research Lab."
"Having a company like Boston Bioprocess, whose bread and butter is actually to churn these strains out and make sure that these fermentations are happening in a repeatable way is very valuable to a company like us."