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Process development and optimization for biotech companies

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OUR HAPPY CLIENTS

A one-stop shop from development to scale up for bioprocesses

Full-suite fermentation and downstream processing services at benchtop and pilot scale.

Our Services

Fermentation optimization to improve yield

Strain testing in conditions replicating commercial manufacturing
Media and process optimization
GRAS oriented process development

Downstream process development to decrease product loss

Wide range of DSP unit operations optimization and scaling
Protein purification by multi-stage TFF
Spray drying development and scale up

Regulatory guidance

Expertise in approval process with FDA
Process towards safety approval
Critical control point identification in process flow

Tech transfer to CMO

Connections to large-scale producers, negotiation assistance, and tech transfer oversight for smooth transition to industrial-scale production

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What can we do?

Plant Capabilities

A one-stop shop to bring your process to commercial scale.

Vessels ranging from 1.5L to 1,500L for stepwise scale up

Solid/liquid, liquid/liquid, slurries. Centrifuges, homogenizer, bead mill, chemical lysis. Strong expertise in industrial-scale cell lysis

Multi-stage TFFs, freeze dryers, spray dryers

HPLC, GC, UV, off-gas, mass spectrometer

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In the News

Featured In

December 07, 2023

iFAB Tech Hub Partners IBRL and Boston Bioprocess Scale Fermentation Tech

The Integrated Bioprocessing Research Laboratory (IBRL) at the University of Illinois Urbana-Champaign and Research Park startup Boston Bioprocess (BBP) are...

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October 19, 2023

Boston Bioprocess and Cauldron Partner to Help Fermentation-based Companies Scale from Lab to Manufacturing

Boston Bioprocess and Cauldron today announce their partnership which aims to overcome one of the biggest challenges for fermentation-based companies today – economically viable paths to...

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