Enable and scale

Process development and optimization for biotech companies
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A one-stop shop from development to scale up for bioprocesses

Full-suite fermentation and downstream processing services at benchtop and pilot scale. 

Our Services

Fermentation optimization to improve yield
Fermentation optimization to improve yield

Strain testing in conditions replicating commercial manufacturing
Media and process optimization
GRAS oriented process development

Downstream process development to decrease product loss
Downstream process development to decrease product loss

Wide range of DSP unit operations optimization and scaling
Protein purification by multi-stage TFF
Spray drying development and scale up

Regulatory guidance
Regulatory guidance

Expertise in approval process with FDA
Process towards safety approval
Critical control point identification in process flow

Tech transfer to CMO
Tech transfer to CMO

Connections to large-scale producers, negotiation assistance, and tech transfer oversight for smooth transition to industrial-scale production

What can we do?

Plant Capabilities

A one-stop shop to bring your process to commercial scale.

Vessels ranging from 1.5L to 1,500L for stepwise scale up

Solid/liquid, liquid/liquid, slurries. Centrifuges, homogenizer, bead mill, chemical lysis. Strong expertise in industrial-scale cell lysis

Multi-stage TFFs, freeze dryers, spray dryers

HPLC, GC, UV, off-gas, mass spectrometer

Fermented Bubbles

Nourish Ingredients Teams with Boston Bioprocess to Scale Animal-Free Fats

Ted Netland Categories: News

Nourish Ingredients, a frontrunner in the burgeoning 'animal-free' specialty fat segment, is teaming with Boston Bioprocess to efficiently scale the most "potent fat molecules" responsible for replicating the "animalic" aroma, flavor, and taste of meat but from wild fungi strains or with the help of synthetic biology and genetically engineered oleaginous yeast strains.

Together the duo are creating a "one stop shop for scaling up fermentation production," which has been notoriously limited, with the ultimate goal of making plant proteins more "authentic" and appealing to consumers, company co-founder and CEO James Petrie told FoodNavigator-USA.

...

Even though Nourish is still operating at a small scale to develop the batches necessary for regulatory approval, Petrie said the company wants to remain asset-light, which makes the scaling "quite challenging."

"Having a company like Boston Bioprocess, whose bread and butter is actually to churn these strains out and make sure that these fermentations are happening in a repeatable way is very valuable to a company like us," he said.

Boston Bioprocess also appealed to Nourish because it not only has developed a scalable process, but it also claims to have improved harvest yield twofold with a method other than the traditional centrifuge.

Read more on FoodNavigator!

Gener8tor AgTech Accelerator Welcomes Fifth Cohort
Boston Bioprocess and Cauldron Partner to Help Fermentation-based Companies Scale from Lab to Manufacturing

BACKED BY

Levervc VC
Gener8tor
FTW Ventures
Siddhi Capital

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